Weba positive ana test (ana +) is virtually a sine qua non for the diagnosis of systemic lupus erythematosus (sle) since more than 95% of patients have a positive. Weba positive result on an ana test means that antinuclear antibodies were found in your blood. You may get a positive result if: You have sle (lupus). You have a different. Weba positive test for ana may help determine the specific type of autoimmune disease that is affecting a patient. A negative test for ana can assist health care.