Dog owners were asked to complete 12. Verkkothis study encompassed an exhaustive representation of canine genetic data, including purebred dogs subjected to intense artificial selection, those. Verkkothis unprecedented dataset will address the genetic underpinnings of domestication, breed formation, aging, behavior and morphological variation. Verkkothe worldwide canine genetics genomics communities recently formed the international consortium of canine genome sequencing, also called the. Verkkoto identify the genetic underpinnings of such traits, we analyze 722 canine whole genome sequences (wgs), documenting over 91 million single nucleotide and small indels, creating a large. Verkkothis work presents a scaffold for canine diversification that positions the domestic dog as an unparalleled system for revealing the genetic origins of. Verkkofrom the 1427 genes in the human tier 1 druggable gene set , we identified 79 genes with their full coding sequence impacted by svs, and 249. Verkkoa genomic ebv is a prediction of a dog's relative genetic merit based solely on its genome sequence. No pedigree information is required.