Webgerd, anxiety, medication effects, and peptic ulcers are just some conditions that may make you feel sick at night. Learn more about the causes and treatment for. Webcauses of nausea at night. There are several reasons why you may experience nausea specifically at night, according to hiten patel, m. d. , a family medicine. Webnighttime nausea is a symptom of various conditions, including pregnancy, anxiety, side effects of medications, gerd, and gastroparesis. I have nausea and feel uneasy. It lasts until i go home and go to bed. 12 votes, 16 comments. I noticed this in the last few.